Coexistence of multiple contaminants in coastal aquatic ecosystems can lead to complicated circumstances in ecotoxicological assessment for biological communities due to potential interaction between contaminants. We chose cadmium (Cd) and phenanthrene (PHE) as representatives of heavy metals and polycyclic aromatic hydrocarbons, respectively. Contamination process was mimicked using coastal water microcosms contaminated by Cd (1 mg/L), PHE (1 mg/L), and their mixture over two weeks.