In this study, we compared the QstR regulon to the TfoX regulon (and TfoY regulon) of V. cholerae in WT strain A1552 and its ?hapR?vpsA derivative using RNA-seq to better understand QstR's function. Overall design: mRNA profiles of a V. cholerae strains A1552-Tn, A1552-TntfoX-strep, A1552-TntfoY-strep, A1552-TnQstR and A1552?vpsA::FRT?hapR::FRT-Tn, A1552?vpsA::FRT?hapR::FRT-TntfoX-strep, A1552?vpsA::FRT?hapR::FRT-TntfoY-strep, A1552?vpsA::FRT?hapR::FRT-TnQstR. 3 independent biological replicates are provided for each bacterial strain. The bacteria were grown to high cell density and in the presence of arabinose as inducer.