A comprehensive set of oceanographic data were collected in Fortune Bay, a broad, mid-latitude fjord located on the south coast of Newfoundland (Canada). The dataset was gathered in partnership with IFREMER who collected data around the adjacent French archipelago of Saint-Pierre and Miquelon. The dataset consists of data from taut-line moorings, land-based stations (a tide gauge and a couple of weather stations) and CTD profiles performed during mooring maintenances (~every 6 months). Parameters covered by the moorings include water column temperature (thermistor chain), salinity (2 points/depths per mooring), dissolved oxygen (on a limited number of moorings, within the surface layer) as well as current profiles (ADCP). Land-based stations monitored water level and temperature (tide gauge) and wind speed and direction, atmospheric pressure, air temperature and solar radiation (weather station). CTD profiles include dissolved oxygen for the most part. The program lasted two full years from May 2015 to May 2017 and sampling interval varied from 1-60 min depending on the instrument.