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Characterisation of biocompatible hydroxy double salts
In our quest to generate novel drug delivery systems, we have synthesised two novel, non-toxic inorganic systems in form of hydroxy couble salts (HDSs) from biocompatiple... -
Aggregation behaviour of PEGylated ibuprofen
In the present study the acidic, anti-inflammatory drug, ibuprofen has been PEGylated using an polyoxyethylene chain of 750 molecular weight. The consequence of this PEGylation... -
Ozonation of organic films at the air-water interface of atmospheric aerosol
The Earth¿s climate is strongly influenced by atmospheric aerosols. Organic surfactant films on these aerosols influences their size, optical properties and ability to act as... -
Neutron diffraction analysis of alpha- and beta-polymorphs of nanoscale metal...
The hydroxides Me(OH)2 of the bivalent transition metals Co, Cu, Fe, Mn, Ni, Cd and Zn play critical roles as sorbents, catalysts or reductants in many environmental and... -
Exploring grain - ice mantle interactions and dynamics for the extraterrestri...
Polycyclic aromatic hydrocarbons (PAHs), a wide class of organic molecules with multiply fused aromatic rings, are ubiquitous in the interstellar medium. In the condensed phase... -
Polymer-surfactant films modified with alkylmethacrylates for structure reten...
We have previously observed formation of polymer-surfactant films at the air-water interface having a range of structures including 2D hexagonal, bicontinuous cubic and lamellar... -
Shaping silica to mesoscale architectures at room-temperature
Hierarchical zeolites with molecular order at both the micropore (<2nm) and mesopore (2-50nm) level are able to combine confinement effects in catalysis without suffering... -
The interaction of cytochrome c with floating bilayers containing negatively ...
As research on apoptosis has gained momentum, the importance of membrane lipids in this crucial cellular process is becoming clear.Previously, we have determined using NR and... -
Surface adsorption of lipopeptides: interfacial layer structure
Lipopeptide surfactants are highly effective at reducing interfacial tension. However, there is a general lack of understanding of the relationship between their molecular... -
Further SANS contrast measurements on important protein/DNA interactions from...
This proposal is to perform further SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an... -
The Interaction of Puroindoline-b with Model Phospholipid Bilayers
Puroindolines are basic cystiene rich proteins which possess unique Trp rich domains which are fully conserved in the predominant isoform Pin-a and partially in Pin-b. This... -
Structure determination of gelled cellulose nanowhisker assemblies
We have developed a new and benign method for the production of cellulose based aerogels, highly porous materials with applications in insulation, drug delivery, gas storage,... -
Self assembly of thermoresponsive gels
Thermoresponsive gels are widely used for tissue engineering and drug delivery applications. They consist of a thermoresponsive polymer that self-assembles in a 3D network when... -
Magnetism of epitaxial Co/CoO nanostructures in the presence of uniaxial anis...
The physics behind the evolution of exchange bias in systems with uniaxial magnetic anisotropy is of high scientific and technological importance. We show unexpected behaviour... -
Phase separation and dewetting of dPS/PVME thin films by specular and off-spe...
We will perform time resolved TOF-reflectivity measurements on deuterated polystyrene (PS) and poly(vinyl methyl ether) (PVME) thin blend films, which has a LCST type phase... -
A neutron reflectometry study of the interaction of octanohydroxamate with iron
The interaction of alkyl hydroxamate with iron is of interest in mineral flotation science, corrosion control and also as a model for microbial siderophore chemistry. Long chain...