Antiretroviral therapy patients in Kolkata, India (n=362) were randomized in one of two conditions: 1) twice-daily IVR calls with messaging, plus a weekly IVR assessment call or 2) an attention control, with only a weekly IVR assessment call. Messages focused on three domains: medically-related, health promotion, and mental health messages. Participants completed assessments at baseline, two-, four-, and six-months.