Data from: Interactions among bacterial strains and fluke genotypes shape virulence of co-infection

Most studies of virulence of infection focus on pairwise host-parasite interactions. However, hosts are almost universally co-infected by several parasite strains and/or genotypes of the same or different species. While theory predicts that co infection favours more virulent parasite genotypes through intensified competition for host resources, knowledge of effects of genotype by genotype (G×G) interactions between unrelated parasite species on virulence of co infection is limited. Here we tested such relationship by challenging rainbow trout with replicated bacterial strains and fluke genotypes both singly and in all possible pairwise combinations. We found that virulence (host mortality) was higher in co infections compared to single-infections. Importantly, we also found that the overall virulence was dependent on the genetic identity of the co-infecting partners so that the outcome of co infection could not be predicted from the respective virulence of single infections. Our results imply that G×G interactions among co infecting parasites may significantly affect host health, add to variance in parasite fitness and thus influence evolutionary dynamics and ecology of disease in unexpected ways.

Identifier
DOI https://doi.org/10.5061/dryad.r21q1
PID https://nbn-resolving.org/urn:nbn:nl:ui:13-90-n7el
Source https://nbn-resolving.org/urn:nbn:nl:ui:13-90-n7el
Metadata Access https://easy.dans.knaw.nl/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=oai:easy.dans.knaw.nl:easy-dataset:90828
Provenance
Creator Louhi, Katja-Riikka; Sundberg, Lotta-Riina; Jokela, Jukka; Karvonen, Anssi
Publisher Data Archiving and Networked Services (DANS)
Publication Year 2015
Rights info:eu-repo/semantics/openAccess; License: http://creativecommons.org/publicdomain/zero/1.0
OpenAccess true
Representation
Resource Type Dataset
Discipline Life Sciences;Medicine