This data set contains the post-processed current profiles collected by means of a vessel-mounted ADCP (on the Spanish vessel RV Ángeles Alvariño) in the Western Mediterranean Sea during August 2016. The TAlPro2016 cruise was part of the MedSHIP programme. During the whole campaign a VM-ADCP (RDI Ocean Surveyor, 150 KHz) works along the whole ship track. The depth range of the current profiler is about 300m. Data acquisition is carried out using the RDI VMDAS software vers. 1.44. The number of bins has been set to 60 m, with a bin size of 8 m. The instrument ran in narrowband mode and was controlled by computers using the conventional RDI VMDAS software under a MS Windows system with a pinging set to be as fast as possible. No interferences with other used acoustical instruments were observed. The ADCP data have been post-processed with the CODAS3 Software System,, which allows extracting data, assigning coordinates, editing and correcting velocity data. Moreover, the data were corrected for errors in the value of sound velocity in water, and misalignment of the instrument with respect to the axis of the ship (about 0.3 degrees). After additional editing, to eliminate suspect values, and those where certain thresholds were surpassed, a netCDF file was created by CODAS3.