The Nunavik Health Study: Determining of dioxin-like compounds in nplasma samples from Inuit adults using the DR-CALUX bioassay

It has been shown that compounds that possess a chemical structure similar to that of dioxin are among the most toxic substances and can provoke a variety effects. However there is little data on exposure of the Canadian Inuit population to these compounds and no information on possible adverse health effects. Inuit people residing in the Arctic receive an unusually high exposure to organochlorines through the traditional/country foods that make up their diet. This project analyzes 1000 plasma samples obtained from Inuit adults participating in the Nunavik Health Study. The analysis will provide data on dioxin-like compound (DLC) body burden in a large sample of the adult Inuit population and it will also allow testing the hypothesis that DLCs are related to chronic diseases such as diabetes and cancer in the North. DR-CALUX bioassay will be used to carry out the analysis because it has been proven to be very cost effective and quick in comparison to conventional methods. These characteristics make the method particularly attractive when dealing with large samples.

Identifier
Source https://www.polardata.ca/pdcsearch/PDCSearchDOI.jsp?doi_id=11085
Metadata Access http://www.polardata.ca/oai/provider?verb=GetRecord&metadataPrefix=fgdc&identifier=11085_fgdc
Provenance
Creator Pierre Ayotte
Publisher Canadian Cryospheric Information Network
Contributor Polar Data Catalogue
Publication Year 2014
Rights Research programs, CCIN, or ArcticNet take no liability for the use or transmission of this data
OpenAccess true
Contact pierre.ayotte(at)inspq.qc.ca; pdc(at)uwaterloo.ca
Representation
Language English
Format Computer file
Discipline Environmental Research
Spatial Coverage (-64.000W, 55.000S, -64.000E, 55.000N)
Temporal Coverage Begin 2004-09-01T00:00:00Z
Temporal Coverage End 2004-09-30T00:00:00Z