Profile hidden Markov models and their underlying multiple sequence alignments for the N- and C-terminal protein domains of expansins.

A profile hidden Markov model (HMM) was derived for each expansin domain from a multiple sequence alignment built from 28 representative protein sequences. The profile HMMs for the N- and C-terminal expansin domain were built by HMMER from multiple sequence alignments (structure-guided). Based on the alignment and on annotations of secondary structures in the Pfam database (entries PF03330.17 for the N-terminal domain and PF01357.20 for the C-terminal domain), the respective domains were manually retrieved.