Monitoring spatial and temporal trends of environmental pollutants in maternal blood in Nunavik

Sociodemographic data were collected using questionnaires administered to all participants. This includes information on age, education, marital status, personal and familial incomes, cigarette, alcohol and drug consumptions of pregnant Inuit women. Contaminant blood levels in Inuit pregnant women from Nunavik were previously measured in 1992 (Santé Québec Health Survey among the Inuit of Nunavik), and in 2004 (Qanuippitaa Health survey). Although the sample sizes were limited (respectively n=11 and n= 26 pregnant women in 1992 and 2004), these data were used to compare the maternal blood contaminant levels between 1992, 2004, and 2012, and assess temporal trends over the last 2 decades. Temporal trend analyses were mainly performed by using linear regression models. The contaminant concentration was defined as the dependent variable and the year of sampling as the main independent variable. Because previous studies reported associations between age and metals or POPS blood levels, the models were adjusted for the age of the participant. Mean age of the pregnant women recruited in 1992, 2004 and 2012 were respectively 23.3 ± 4.8 years, 26.4 ± 5.6 years and 24.9 ± 5.6 years. Mercury and lead: Statistical analyses suggest that maternal blood concentrations in mercury and lead significantly decreased between 1992 and 2012. Temporal trends for POPs were also investigated. Due to limited sample sizes, missing data and difficulties related to limit detection values, comparisons of POPS maternal blood levels between 1992, 2004 and 2012 were not always possible. Nevertheless we were able to conduct the analyses for several legacy POPs. According to our model adjusted for age, p.p'-DDE p.'¿-DDT, oxychlordane, trans-nonachlor, mirex, cis-nonachlor, hexachlorobenzene, PCB-118, PCB-138, PCB-153, PCB-170 and PCB-180 plasma concentrations significantly decreased between 1992 and 2012. Statistical analyses for fatty acids were performed by using Student's t-tests and Kruskal-Wallis non-parametric tests. Results are shown in table 5. No significant changes in DPA and DHA levels were observed between 2004 and 2012. However, the EPA levels, EPA+DHA contents and n-3/n-6 PUFA ratio seem to have significantly dropped over the last 8 years. EPA+DHA and n3/n6 ratio are both frequently considered as biomarkers of dietary marine food intakes (Jeppesen et al 2012). As a result, their decreases suggest a decline of marine food consumption by Inuit pregnant women.

Identifier
Source https://www.polardata.ca/pdcsearch/PDCSearchDOI.jsp?doi_id=12428
Metadata Access http://www.polardata.ca/oai/provider?verb=GetRecord&metadataPrefix=fgdc&identifier=12428_fgdc
Provenance
Creator Dewailly, Éric; Ayotte, Pierre; Dallaire, Renée; Muckle, Gina
Publisher Canadian Cryospheric Information Network
Contributor Polar Data Catalogue
Publication Year 2015
Rights Research programs, CCIN, or ArcticNet take no liability for the use or transmission of this data
OpenAccess true
Contact suzanne.cote(at)crchul.ulaval.ca; pdc(at)uwaterloo.ca
Representation
Language English
Format Computer file
Discipline Environmental Research
Spatial Coverage (-64.000W, 55.000S, -64.000E, 55.000N)
Temporal Coverage Begin 2011-01-01T00:00:00Z
Temporal Coverage End 2015-12-31T00:00:00Z